| Cash Flow | 2025-09-30 | 2025-06-30 |
|---|---|---|
| Net loss | -383,991 | -257,089 |
| Depreciation and amortization | 8,317 | 5,370 |
| Stockbased compensation expense | 75,682 | 50,547 |
| Net accretion of discounts on marketable securities | 8,611 | 6,585 |
| Non-cash adjustment to operating lease expense | 3,305 | 2,161 |
| Right-of-use asset amortization for finance lease | 2,713 | 1,798 |
| Non-cash gain from divestiture of small molecule programs | 0 | 0 |
| Prepaid expenses and other current assets | 2,287 | 3,650 |
| Other non-current assets | -1,305 | -3,022 |
| Accounts payable | -4,112 | -43 |
| Accruals and other current liabilities | -12,262 | -14,151 |
| Deferred research and development funding liability | 12,489 | 16,176 |
| Net cash used in operating activities | -314,062 | -206,766 |
| Purchases of marketable securities | 188,555 | 137,926 |
| Maturities and sales of marketable securities | 431,046 | 323,965 |
| Purchases of property and equipment | 7,978 | 9,356 |
| Net cash provided by (used in) investing activities | 234,513 | 176,683 |
| Proceeds from issuance of common stock and pre-funded warrants, net of issuance costs of 480 | 0 | 0 |
| Proceeds from exercise of awards under equity incentive plans | 5,235 | 4,652 |
| Payments for finance lease right-of-use asset | 8,152 | 6,791 |
| Net cash (used in) provided by financing activities | -2,917 | -2,139 |
| Net decrease in cash, cash equivalents and restricted cash | -82,466 | -32,222 |
| Cash and cash equivalents at beginning of period | 176,535 | - |
| Cash and cash equivalents at end of period | 94,069 | - |
Denali Therapeutics Inc. (DNLI)
Denali Therapeutics Inc. (DNLI)